Human Recombinant VEGFA
Price:
$1,216.71
Product Name : Human Recombinant VEGFA
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less defined and is thought to modulate the VEGFR2 signaling.
This recombinant protein can be used for biological assays. For research use only.
| Protein/peptide name | VEGFA |
| Protein synonyms | Vascular Endothelial Growth Factor Isoform 165,VEGF 165,VEGF165 |
| Protein/peptide type | Recombinant |
| Species | Human |
| Source | Cells |
| Sequence | Ala27-Arg191 |
| Endotoxin content | <0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
| Purity | > 95% as determined by reducing SDS-PAGE |
| Formulation | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Molecular weight | 19.1 kD |
| Storage conditions | Lyophilized protein should be stored at ?20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at ?20 °C for 3 months. |
| Tested applications | Bioassay |
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