Human Recombinant VEGF 165
Product Name : Human Recombinant VEGF 165
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Human VEGF 165 is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
| Protein/peptide name | VEGF 165 |
| Protein synonyms | Folliculostellate cell-derived growth factor,Vascular Endothelial Growth Factor,VEGF-A,Glioma-derived endothelial cell mitogen |
| Protein/peptide type | Recombinant |
| Species | Human |
| Source | E. coli |
| Conjugation | Unconjugated |
| Gene ID | 7422 |
| Sequence | APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR |
| Animal-free | Y |
| Endotoxin level | low |
| Biological activity | Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml. |
| Purity | 98% |
| Formulation | Lyophilized |
| Molecular weight | 38.2 kDa |
| Shipping temperature | Ambient |
| Molecular weight | 38.2 kDa |