Human Recombinant TEM7
Price:
$996.93
Product Name : Human Recombinant TEM7
Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs).
- Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.
| Protein/peptide name | TEM7 |
| Protein synonyms | TEM3,Tumor Endothelial Marker 7,Plexin Domain-Containing Protein 1,TEM7,Tumor Endothelial Marker 3,PLXDC1 |
| Protein/peptide type | Recombinant |
| Species | Human |
| Source | Cells |
| Sequence | Leu19-Thr426 |
| Endotoxin content | <0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
| Purity | > 95% as determined by reducing SDS-PAGE |
| Formulation | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 5% Threhalose, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Molecular weight | 46.53 kD |
| Storage conditions | Lyophilized protein should be stored at ?20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at ?20 °C for 3 months. |
| Tag sequence | C-6 His tag |
| Tested applications | Bioassay |
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