Anti-TEK Rabbit Polyclonal Antibody
Price:
$712.11
Product Name : Anti-TEK Rabbit Polyclonal Antibody
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Western Blot: 1:500~1:1000
| Antigen symbol | TEK |
| Antigen name | TEK tyrosine kinase, endothelial |
| Antigen synonyms | TEK |
| Antibody type | Primary |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Reactivity | Human,Mouse |
| Host | Rabbit |
| Gene ID | Q02763 |
| Isotype | IgG |
| Western blot | Yes |
| Modification | Tyr 992 |
| Immunogen | TIE2 (phospho Tyr992) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 992 (E-V-Y (p)-V-K) derived from Human TIE2. |
| Form | Liquid |
| Molecular weight | 126 kDa |
| Purification | Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Concentration | 1 mg/mL |
| Storage buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage temperature | Store antibody at –20 °C for up to one year. |
| Shipping temperature | 4 °C |
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