Anti-COL4A1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Price:
$1,057.62
Product Name : Anti-COL4A1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
Recommended Dilutions: IF(IHC-P): 1:50-200
| Antigen symbol | COL4A1 |
| Antigen name | Collagen, type IV, alpha 1 |
| Antigen synonyms | BSVD,RATOR |
| Antibody type | Primary |
| Clonality | Polyclonal |
| Conjugation | FITC (Fluorescein Isothiocyanate) |
| Reactivity | Human,Rat,Mouse |
| Host | Rabbit |
| Gene ID | 1282 |
| Isotype | IgG |
| ImmunoChemistry | Yes |
| Immunogen | 1620-1665/1669 |
| Form | liquid |
| Purification | Purified by Protein A |
| Concentration | 1 ?g/?l |
| Cross adsorption | No |
| Storage buffer | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months. |
| Storage temperature | Store at 4°C for 12 months |
| Shipping temperature | 4°C |
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